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ASMT ASMT AANAT AANAT CYP1A2 CYP1A2 ALDH3A2 ALDH3A2 CYP1A1 CYP1A1 CYP1B1 CYP1B1 IDO2 IDO2 ALDH9A1 ALDH9A1 ALDH7A1 ALDH7A1 AOX1 AOX1 AOX2 AOX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ASMTAcetylserotonin O-methyltransferase; Catalyzes the transfer of a methyl group onto N- acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. (346 aa)    
Predicted Functional Partners:
AANAT
Serotonin N-acetyltransferase; Catalyzes the N-acetylation of serotonin into N- acetylserotonin; Belongs to the acetyltransferase family. AANAT subfamily.
   
 
 0.998
CYP1A2
Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
   
 
 0.936
ALDH3A2
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
 0.935
CYP1A1
Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
     
 0.920
CYP1B1
Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.
     
 0.920
IDO2
Uncharacterized protein.
   
 
 0.912
ALDH9A1
Aldehyde dehydrogenase 9 family member A1; Belongs to the aldehyde dehydrogenase family.
     
 0.908
ALDH7A1
Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family.
     
 0.904
AOX1
Uncharacterized protein.
     
 0.903
AOX2
Uncharacterized protein.
     
 0.903
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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