node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PAAF1 | PSMC1 | ENSGALP00000027934 | ENSGALP00000017347 | Proteasomal ATPase-associated factor 1; Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core. Belongs to the WD repeat PAAF1/RPN14 family. | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | 0.823 |
PAAF1 | PSMC2 | ENSGALP00000027934 | ENSGALP00000060323 | Proteasomal ATPase-associated factor 1; Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core. Belongs to the WD repeat PAAF1/RPN14 family. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.948 |
PAAF1 | PSMC3 | ENSGALP00000027934 | ENSGALP00000037708 | Proteasomal ATPase-associated factor 1; Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core. Belongs to the WD repeat PAAF1/RPN14 family. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.934 |
PAAF1 | PSMC5 | ENSGALP00000027934 | ENSGALP00000070654 | Proteasomal ATPase-associated factor 1; Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core. Belongs to the WD repeat PAAF1/RPN14 family. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.994 |
PAAF1 | PSMD10 | ENSGALP00000027934 | ENSGALP00000013470 | Proteasomal ATPase-associated factor 1; Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core. Belongs to the WD repeat PAAF1/RPN14 family. | ANK_REP_REGION domain-containing protein. | 0.994 |
PAAF1 | PSMD12 | ENSGALP00000027934 | ENSGALP00000041149 | Proteasomal ATPase-associated factor 1; Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core. Belongs to the WD repeat PAAF1/RPN14 family. | PCI domain-containing protein. | 0.932 |
PAAF1 | PSMD13 | ENSGALP00000027934 | ENSGALP00000054631 | Proteasomal ATPase-associated factor 1; Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core. Belongs to the WD repeat PAAF1/RPN14 family. | 26S proteasome non-ATPase regulatory subunit 13; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. | 0.880 |
PAAF1 | PSMD14 | ENSGALP00000027934 | ENSGALP00000018120 | Proteasomal ATPase-associated factor 1; Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core. Belongs to the WD repeat PAAF1/RPN14 family. | MPN domain-containing protein. | 0.932 |
PAAF1 | PSMD2 | ENSGALP00000027934 | ENSGALP00000010153 | Proteasomal ATPase-associated factor 1; Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core. Belongs to the WD repeat PAAF1/RPN14 family. | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.895 |
PAAF1 | PSMD7 | ENSGALP00000027934 | ENSGALP00000000999 | Proteasomal ATPase-associated factor 1; Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core. Belongs to the WD repeat PAAF1/RPN14 family. | Proteasome 26S subunit, non-ATPase 7. | 0.933 |
PSMC1 | PAAF1 | ENSGALP00000017347 | ENSGALP00000027934 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | Proteasomal ATPase-associated factor 1; Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core. Belongs to the WD repeat PAAF1/RPN14 family. | 0.823 |
PSMC1 | PSMC2 | ENSGALP00000017347 | ENSGALP00000060323 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.999 |
PSMC1 | PSMC3 | ENSGALP00000017347 | ENSGALP00000037708 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.999 |
PSMC1 | PSMC5 | ENSGALP00000017347 | ENSGALP00000070654 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.999 |
PSMC1 | PSMD10 | ENSGALP00000017347 | ENSGALP00000013470 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | ANK_REP_REGION domain-containing protein. | 0.996 |
PSMC1 | PSMD12 | ENSGALP00000017347 | ENSGALP00000041149 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | PCI domain-containing protein. | 0.999 |
PSMC1 | PSMD13 | ENSGALP00000017347 | ENSGALP00000054631 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | 26S proteasome non-ATPase regulatory subunit 13; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. | 0.999 |
PSMC1 | PSMD14 | ENSGALP00000017347 | ENSGALP00000018120 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | MPN domain-containing protein. | 0.999 |
PSMC1 | PSMD2 | ENSGALP00000017347 | ENSGALP00000010153 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.999 |
PSMC1 | PSMD7 | ENSGALP00000017347 | ENSGALP00000000999 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | Proteasome 26S subunit, non-ATPase 7. | 0.999 |