STRINGSTRING
LPL LPL MOGAT1 MOGAT1 DGKI DGKI DGKZ DGKZ LPIN1 LPIN1 PLPP3 PLPP3 PNPLA2 PNPLA2 LPIN2 LPIN2 PLPP1 PLPP1 PLPP5 PLPP5 PLPP2 PLPP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (490 aa)    
Predicted Functional Partners:
MOGAT1
Monoacylglycerol O-acyltransferase 1.
     
 0.928
DGKI
Diacylglycerol kinase.
   
 
 0.923
DGKZ
Diacylglycerol kinase.
   
 
 0.923
LPIN1
Lipin 1.
   
 
 0.910
PLPP3
acidPPc domain-containing protein.
   
  0.906
PNPLA2
PNPLA2/ATGL.
   
 
 0.905
LPIN2
LNS2 domain-containing protein.
   
 
 0.905
PLPP1
Phospholipid phosphatase 1.
   
  0.904
PLPP5
Phospholipid phosphatase 5.
    
  0.903
PLPP2
Phospholipid phosphatase 2.
    
  0.903
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (22%) [HD]