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ASL1 ASL1 ASS1 ASS1 OAT OAT OTC OTC TRMU TRMU ALDH18A1 ALDH18A1 ARG2 ARG2 CPS1 CPS1 CRYGN CRYGN AGMAT AGMAT TMEM116 TMEM116
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ASL1Delta-1 crystallin; Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. (501 aa)    
Predicted Functional Partners:
ASS1
Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family.
 
 0.994
OAT
Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.987
OTC
Ornithine carbamoyltransferase, mitochondrial.
 
  
 0.811
TRMU
Mitochondrial tRNA-specific 2-thiouridylase 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. Belongs to the MnmA/TRMU family.
    
  0.804
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
     
 0.773
ARG2
Arginase.
     
 0.754
CPS1
Uncharacterized protein.
  
 
 0.688
CRYGN
Uncharacterized protein; Belongs to the beta/gamma-crystallin family.
      
 0.666
AGMAT
Agmatinase, mitochondrial; Belongs to the arginase family. Agmatinase subfamily.
     
 0.666
TMEM116
Transmembrane protein 116.
  
 
 0.655
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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