node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CFTR | F7D8T5_ORNAN | ENSOANP00000013971 | ENSOANP00000019893 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | EBP50_C domain-containing protein. | 0.936 |
CFTR | GOPC | ENSOANP00000013971 | ENSOANP00000005853 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | PDZ domain-containing protein. | 0.872 |
CFTR | PRKAA1 | ENSOANP00000013971 | ENSOANP00000028274 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Non-specific serine/threonine protein kinase. | 0.916 |
CFTR | PRKAB2 | ENSOANP00000013971 | ENSOANP00000005129 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Protein kinase AMP-activated non-catalytic subunit beta 2. | 0.914 |
CFTR | PRKACA | ENSOANP00000013971 | ENSOANP00000010075 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Protein kinase cAMP-activated catalytic subunit alpha. | 0.934 |
CFTR | PRKACB | ENSOANP00000013971 | ENSOANP00000022714 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Uncharacterized protein. | 0.934 |
CFTR | PRKAG1 | ENSOANP00000013971 | ENSOANP00000033017 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | CBS domain-containing protein. | 0.901 |
CFTR | PRKAG2 | ENSOANP00000013971 | ENSOANP00000009864 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Protein kinase AMP-activated non-catalytic subunit gamma 2. | 0.904 |
CFTR | PRKAG3 | ENSOANP00000013971 | ENSOANP00000015045 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | CBS domain-containing protein. | 0.903 |
CFTR | TJP1-2 | ENSOANP00000013971 | ENSOANP00000027343 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | PDZ domain-containing protein. | 0.918 |
F7D8T5_ORNAN | CFTR | ENSOANP00000019893 | ENSOANP00000013971 | EBP50_C domain-containing protein. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | 0.936 |
F7D8T5_ORNAN | GOPC | ENSOANP00000019893 | ENSOANP00000005853 | EBP50_C domain-containing protein. | PDZ domain-containing protein. | 0.508 |
GOPC | CFTR | ENSOANP00000005853 | ENSOANP00000013971 | PDZ domain-containing protein. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | 0.872 |
GOPC | F7D8T5_ORNAN | ENSOANP00000005853 | ENSOANP00000019893 | PDZ domain-containing protein. | EBP50_C domain-containing protein. | 0.508 |
PRKAA1 | CFTR | ENSOANP00000028274 | ENSOANP00000013971 | Non-specific serine/threonine protein kinase. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | 0.916 |
PRKAA1 | PRKAB2 | ENSOANP00000028274 | ENSOANP00000005129 | Non-specific serine/threonine protein kinase. | Protein kinase AMP-activated non-catalytic subunit beta 2. | 0.996 |
PRKAA1 | PRKACA | ENSOANP00000028274 | ENSOANP00000010075 | Non-specific serine/threonine protein kinase. | Protein kinase cAMP-activated catalytic subunit alpha. | 0.924 |
PRKAA1 | PRKACB | ENSOANP00000028274 | ENSOANP00000022714 | Non-specific serine/threonine protein kinase. | Uncharacterized protein. | 0.922 |
PRKAA1 | PRKAG1 | ENSOANP00000028274 | ENSOANP00000033017 | Non-specific serine/threonine protein kinase. | CBS domain-containing protein. | 0.977 |
PRKAA1 | PRKAG2 | ENSOANP00000028274 | ENSOANP00000009864 | Non-specific serine/threonine protein kinase. | Protein kinase AMP-activated non-catalytic subunit gamma 2. | 0.990 |