STRINGSTRING
THY1 THY1 ITGAM ITGAM ITGB2 ITGB2 CD34 CD34 ARHGAP5 ARHGAP5 ARHGAP35 ARHGAP35 CD44 CD44 CD19 CD19 CD79A CD79A PSEN1 PSEN1 POU5F1 POU5F1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THY1Thy-1 membrane glycoprotein; May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. (177 aa)    
Predicted Functional Partners:
ITGAM
Integrin subunit alpha M; Belongs to the integrin alpha chain family.
   
 
 0.969
ITGB2
Integrin beta.
   
 
 0.936
CD34
CD34 molecule.
      
 0.910
ARHGAP5
Uncharacterized protein.
     
  0.900
ARHGAP35
Rho GTPase activating protein 35.
     
  0.900
CD44
Phagocytic glycoprotein I.
      
 0.872
CD19
CD19 molecule.
      
 0.825
CD79A
CD79a molecule.
   
  
 0.785
PSEN1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
      
 0.706
POU5F1
POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily.
      
 0.702
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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