Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DVL2 | DVL3 | ENSPPYP00000008887 | ENSPPYP00000016042 | DVL2 isoform 1. | DVL3 isoform 1. | 0.988 |
| DVL2 | FZD6 | ENSPPYP00000008887 | ENSPPYP00000021096 | DVL2 isoform 1. | Frizzled-6; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to i [...] | 0.981 |
| DVL2 | LRP6 | ENSPPYP00000008887 | ENSPPYP00000024153 | DVL2 isoform 1. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.960 |
| DVL2 | RNF43 | ENSPPYP00000008887 | ENSPPYP00000009250 | DVL2 isoform 1. | RNF43 isoform 2. | 0.648 |
| DVL2 | WNT1 | ENSPPYP00000008887 | ENSPPYP00000005109 | DVL2 isoform 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.636 |
| DVL2 | WNT11 | ENSPPYP00000008887 | ENSPPYP00000004224 | DVL2 isoform 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.746 |
| DVL2 | WNT4 | ENSPPYP00000008887 | ENSPPYP00000002030 | DVL2 isoform 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.541 |
| DVL2 | WNT5A | ENSPPYP00000008887 | ENSPPYP00000015420 | DVL2 isoform 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.966 |
| DVL2 | WNT5B | ENSPPYP00000008887 | ENSPPYP00000004719 | DVL2 isoform 1. | Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity); Belongs to the Wnt family. | 0.587 |
| DVL2 | ZNRF3 | ENSPPYP00000008887 | ENSPPYP00000013028 | DVL2 isoform 1. | ZNRF3 isoform 2. | 0.427 |
| DVL3 | DVL2 | ENSPPYP00000016042 | ENSPPYP00000008887 | DVL3 isoform 1. | DVL2 isoform 1. | 0.988 |
| DVL3 | FZD6 | ENSPPYP00000016042 | ENSPPYP00000021096 | DVL3 isoform 1. | Frizzled-6; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to i [...] | 0.972 |
| DVL3 | LRP6 | ENSPPYP00000016042 | ENSPPYP00000024153 | DVL3 isoform 1. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.904 |
| DVL3 | WNT1 | ENSPPYP00000016042 | ENSPPYP00000005109 | DVL3 isoform 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.703 |
| DVL3 | WNT11 | ENSPPYP00000016042 | ENSPPYP00000004224 | DVL3 isoform 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.620 |
| DVL3 | WNT4 | ENSPPYP00000016042 | ENSPPYP00000002030 | DVL3 isoform 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.486 |
| DVL3 | WNT5A | ENSPPYP00000016042 | ENSPPYP00000015420 | DVL3 isoform 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.774 |
| DVL3 | WNT5B | ENSPPYP00000016042 | ENSPPYP00000004719 | DVL3 isoform 1. | Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity); Belongs to the Wnt family. | 0.563 |
| FZD6 | DVL2 | ENSPPYP00000021096 | ENSPPYP00000008887 | Frizzled-6; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to i [...] | DVL2 isoform 1. | 0.981 |
| FZD6 | DVL3 | ENSPPYP00000021096 | ENSPPYP00000016042 | Frizzled-6; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to i [...] | DVL3 isoform 1. | 0.972 |
page 1 of 5