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ALDH3A2 ALDH3A2 AKR1B1 AKR1B1 MAOA MAOA ABAT ABAT AOC1 AOC1 EHHADH EHHADH ACSS1 ACSS1 ACSS2 ACSS2 AGXT2 AGXT2 AKR1B10 AKR1B10 AKR1A1 AKR1A1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Known Interactions
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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ALDH3A2Aldehyde dehydrogenase family 3 member A2; Catalyzes the oxidation of medium and long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid. (491 aa)    
Predicted Functional Partners:
AKR1B1
Aldo-keto reductase family 1 member B.
   
 0.958
MAOA
Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity).
  
 
 0.952
ABAT
ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.945
AOC1
Amine oxidase.
   
 0.945
EHHADH
Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.944
ACSS1
Acetyl-coenzyme A synthetase.
  
 0.943
ACSS2
ACSS2 isoform 8.
  
 0.943
AGXT2
Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.939
AKR1B10
Aldo-keto reductase family 1 member B10.
   
 0.935
AKR1A1
Aldo-keto reductase family 1 member A1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids, with a preference for negatively charged substrates, such as glucuronate and succinic semialdehyde (By similarity). Functions as a detoxifiying enzyme by reducing a range of toxic aldehydes. Reduces methylglyoxal and 3-deoxyglucosone, which are present at elevated levels under hypergly [...]
   
 0.934
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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