STRING 10 
  VCL protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
VCL
vinculin; Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion (1134 aa)
(Homo sapiens)
Predicted Functional Partners:
PXN
paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion [...] (591 aa)
     0.999
SORBS1
sorbin and SH3 domain containing 1 (1292 aa)
     0.999
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); Non-receptor protein tyrosin [...] (536 aa)
     0.998
CDH1
cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion prot [...] (882 aa)
     0.998
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa; Associates with the cytoplasmic domain [...] (906 aa)
    0.998
RAVER1
ribonucleoprotein, PTB-binding 1; Cooperates with PTBP1 to modulate regulated alternative splic [...] (756 aa)
      0.997
TNS1
tensin 1; May be involved in cell migration, cartilage development and in linking signal transd [...] (1735 aa)
     0.997
TLN1
talin 1; Probably involved in connections of major cytoskeletal structures to the plasma membra [...] (2541 aa)
     0.996
ACTN1
actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety o [...] (914 aa)
    0.995
PTK2
PTK2 protein tyrosine kinase 2; Non-receptor protein-tyrosine kinase that plays an essential ro [...] (1065 aa)
     0.995
 
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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