STRINGSTRING
OCEL1 OCEL1 ABHD8 ABHD8 TMEM205 TMEM205 TLCD1 TLCD1 CLDND1 CLDND1 POLR2C POLR2C DYDC2 DYDC2 SMIM29 SMIM29
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OCEL1occludin/ELL domain containing 1; Belongs to the ELL/occludin family. (264 aa)    
Predicted Functional Partners:
ABHD8
Protein ABHD8; Abhydrolase domain containing 8; Belongs to the AB hydrolase superfamily.
   
  
 0.477
TMEM205
Transmembrane protein 205; In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin.
   
  
 0.470
TLCD1
TLC domain-containing protein 1; Regulates the composition and fluidity of the plasma membrane. Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity. Does not appear to have any effect on LCPUFA synthesis.
   
  
 0.436
CLDND1
Claudin domain containing 1.
      
 0.429
POLR2C
DNA-directed RNA polymerase II subunit RPB3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft (By similarity).
   
 
 0.423
DYDC2
DPY30 domain containing 2; Belongs to the dpy-30 family.
      
 0.415
SMIM29
Small integral membrane protein 29.
   
  
 0.401
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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