STRING 9.1 
  IL12B protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated killer cells, and stimulate the production of IFN-gamma by resting PBMC (328 aa)
(Homo sapiens)
Predicted Functional Partners:
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation fact [...] (253 aa)
     0.999
IL23A
interleukin 23, alpha subunit p19; Associates with IL12B to form the IL-23 interleukin, an hete [...] (189 aa)
     0.998
IL12RB1
interleukin 12 receptor, beta 1; Functions as an interleukin receptor which binds interleukin-1 [...] (381 aa)
     0.993
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; NF-kappa-B is a pleiotrop [...] (969 aa)
      0.981
IL12RB2
interleukin 12 receptor, beta 2; Receptor for interleukin-12. This subunit is the signaling com [...] (862 aa)
     0.979
IFNG
interferon, gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamm [...] (166 aa)
      0.970
IL6
interleukin 6 (interferon, beta 2); Cytokine with a wide variety of biological functions. It is [...] (212 aa)
     0.960
IL23R
interleukin 23 receptor; Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL2 [...] (629 aa)
      0.958
CD4
CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regul [...] (458 aa)
      0.949
STAT1
signal transducer and activator of transcription 1, 91kDa; Signal transducer and activator of t [...] (750 aa)
      0.946
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (24%)
Permalink