STRING 10 
  RARA protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
RARA
retinoic acid receptor, alpha; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcrip [...] (462 aa)
(Homo sapiens)
Predicted Functional Partners:
NCOR2
nuclear receptor corepressor 2; Transcriptional corepressor of NR4A2/NURR1 and acts through his [...] (2514 aa)
     0.999
NCOA1
nuclear receptor coactivator 1 (1441 aa)
     0.999
PML
promyelocytic leukemia (882 aa)
     0.999
NCOR1
nuclear receptor corepressor 1; Mediates transcriptional repression by certain nuclear receptor [...] (2440 aa)
      0.999
NCOA3
nuclear receptor coactivator 3 (1424 aa)
     0.999
NRIP1
nuclear receptor interacting protein 1; Modulates transcriptional activation by steroid recepto [...] (1158 aa)
      0.998
NCOA2
nuclear receptor coactivator 2; Transcriptional coactivator for steroid receptors and nuclear r [...] (1464 aa)
     0.997
MED1
mediator complex subunit 1; Component of the Mediator complex, a coactivator involved in the re [...] (1581 aa)
     0.996
RXRG
retinoid X receptor, gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterod [...] (463 aa)
    0.996
KAT2B
K(lysine) acetyltransferase 2B; Functions as a histone acetyltransferase (HAT) to promote trans [...] (832 aa)
     0.993
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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