STRING 9.1 
  LEMD3 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
LEMD3
LEM domain containing 3; Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest (911 aa)
(Homo sapiens)
Predicted Functional Partners:
SMAD2
SMAD family member 2; Transcriptional modulator activated by TGF-beta and activin type 1 recept [...] (467 aa)
      0.978
EMD
emerin; Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates a [...] (254 aa)
       0.947
PIGN
phosphatidylinositol glycan anchor biosynthesis, class N; Ethanolamine phosphate transferase in [...] (931 aa)
       0.798
WIF1
WNT inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved i [...] (379 aa)
       0.798
SMAD1
SMAD family member 1; Transcriptional modulator activated by BMP (bone morphogenetic proteins) [...] (465 aa)
      0.755
SMAD4
SMAD family member 4; Common mediator of signal transduction by TGF-beta (transforming growth f [...] (552 aa)
     0.743
SMAD3
SMAD family member 3; Transcriptional modulator activated by TGF-beta (transforming growth fact [...] (425 aa)
      0.740
BCLAF1
BCL2-associated transcription factor 1; Death-promoting transcriptional repressor (920 aa)
      0.680
ANKLE1
ankyrin repeat and LEM domain containing 1 (615 aa)
       0.609
BANF1
barrier to autointegration factor 1; Plays fundamental roles in nuclear assembly, chromatin org [...] (89 aa)
       0.609
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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