STRINGSTRING
DEFB106A DEFB106A DEFB107A DEFB107A DEFB105A DEFB105A DEFB104A DEFB104A SPAG11B SPAG11B DEFB106B DEFB106B DEFB103A DEFB103A DEFB108B DEFB108B DEFB105B DEFB105B PRR23D2 PRR23D2 PRR23D1 PRR23D1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB106ADefensin beta 106A. (65 aa)    
Predicted Functional Partners:
DEFB107A
Beta-defensin 107; Has antibacterial activity.
   
  
 0.919
DEFB105A
Beta-defensin 105; Has antibacterial activity.
   
  
 0.903
DEFB104A
Beta-defensin 104; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103; Belongs to the beta-defensin family.
   
  
 0.849
SPAG11B
Sperm associated antigen 11B.
      
 0.848
DEFB106B
Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family.
   
  
0.820
DEFB103A
Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.
      
 0.808
DEFB108B
Beta-defensin 108B; Has antibacterial activity.
      
 0.799
DEFB105B
Defensin beta 105B.
   
  
 0.670
PRR23D2
Proline-rich protein 23D1; Proline rich 23 domain containing 2; Belongs to the PRR23 family.
      
 0.663
PRR23D1
Proline rich 23 domain containing 1.
      
 0.663
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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