node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABHD1 | C3orf18 | ENSP00000326491 | ENSP00000349732 | Protein ABHD1; Abhydrolase domain containing 1; Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | 0.522 |
C1orf198 | C3orf18 | ENSP00000355623 | ENSP00000349732 | Uncharacterized protein C1orf198; Chromosome 1 open reading frame 198. | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | 0.515 |
C1orf198 | HSPA9 | ENSP00000355623 | ENSP00000297185 | Uncharacterized protein C1orf198; Chromosome 1 open reading frame 198. | Stress-70 protein, mitochondrial; Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging (By similarity). Belongs to the heat shock protein 70 family. | 0.729 |
C1orf198 | TIMM23 | ENSP00000355623 | ENSP00000464522 | Uncharacterized protein C1orf198; Chromosome 1 open reading frame 198. | Mitochondrial import inner membrane translocase subunit Tim23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane; Belongs to the Tim17/Tim22/Tim23 family. | 0.790 |
C1orf198 | TIMM23B | ENSP00000355623 | ENSP00000363211 | Uncharacterized protein C1orf198; Chromosome 1 open reading frame 198. | Translocase of inner mitochondrial membrane 23 homolog B. | 0.790 |
C3orf18 | ABHD1 | ENSP00000349732 | ENSP00000326491 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | Protein ABHD1; Abhydrolase domain containing 1; Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. | 0.522 |
C3orf18 | C1orf198 | ENSP00000349732 | ENSP00000355623 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | Uncharacterized protein C1orf198; Chromosome 1 open reading frame 198. | 0.515 |
C3orf18 | COX5B | ENSP00000349732 | ENSP00000258424 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | Cytochrome c oxidase subunit 5B, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] | 0.613 |
C3orf18 | HSPA9 | ENSP00000349732 | ENSP00000297185 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | Stress-70 protein, mitochondrial; Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging (By similarity). Belongs to the heat shock protein 70 family. | 0.586 |
C3orf18 | MRPL45 | ENSP00000349732 | ENSP00000484903 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | Mitochondrial ribosomal protein L45. | 0.528 |
C3orf18 | PAM16 | ENSP00000349732 | ENSP00000315693 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | Mitochondrial import inner membrane translocase subunit TIM16; Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity; Belongs to the TIM16/PAM16 family. | 0.739 |
C3orf18 | STK19 | ENSP00000349732 | ENSP00000364482 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | Serine/threonine-protein kinase 19; Serine/threonine-protein kinase that acts as a key regulator of NRAS signaling by mediating phosphorylation of NRAS at 'Ser-89', thereby enhancing NRAS-binding to its downstream effectors. Belongs to the STK19 family. | 0.601 |
C3orf18 | TIMM10 | ENSP00000349732 | ENSP00000257245 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | Mitochondrial import inner membrane translocase subunit Tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. Belongs to the small Tim family. | 0.514 |
C3orf18 | TIMM23 | ENSP00000349732 | ENSP00000464522 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | Mitochondrial import inner membrane translocase subunit Tim23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane; Belongs to the Tim17/Tim22/Tim23 family. | 0.567 |
C3orf18 | TIMM23B | ENSP00000349732 | ENSP00000363211 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | Translocase of inner mitochondrial membrane 23 homolog B. | 0.567 |
COX5B | C3orf18 | ENSP00000258424 | ENSP00000349732 | Cytochrome c oxidase subunit 5B, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | 0.613 |
COX5B | HSPA9 | ENSP00000258424 | ENSP00000297185 | Cytochrome c oxidase subunit 5B, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] | Stress-70 protein, mitochondrial; Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging (By similarity). Belongs to the heat shock protein 70 family. | 0.925 |
COX5B | TIMM23 | ENSP00000258424 | ENSP00000464522 | Cytochrome c oxidase subunit 5B, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] | Mitochondrial import inner membrane translocase subunit Tim23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane; Belongs to the Tim17/Tim22/Tim23 family. | 0.898 |
COX5B | TIMM23B | ENSP00000258424 | ENSP00000363211 | Cytochrome c oxidase subunit 5B, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] | Translocase of inner mitochondrial membrane 23 homolog B. | 0.874 |
HSPA9 | C1orf198 | ENSP00000297185 | ENSP00000355623 | Stress-70 protein, mitochondrial; Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging (By similarity). Belongs to the heat shock protein 70 family. | Uncharacterized protein C1orf198; Chromosome 1 open reading frame 198. | 0.729 |