node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BTBD17 | TTC13 | ENSP00000364515 | ENSP00000355621 | BTB/POZ domain-containing protein 17; BTB domain containing 17. | Tetratricopeptide repeat domain 13. | 0.491 |
CDC42EP5 | TTC13 | ENSP00000301200 | ENSP00000355621 | Cdc42 effector protein 5; Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42 (By similarity); Belongs to the BORG/CEP family. | Tetratricopeptide repeat domain 13. | 0.518 |
FAM122B | TTC13 | ENSP00000487221 | ENSP00000355621 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | Tetratricopeptide repeat domain 13. | 0.496 |
LEO1 | TTC13 | ENSP00000299601 | ENSP00000355621 | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser- 5'-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox [...] | Tetratricopeptide repeat domain 13. | 0.475 |
MT-ND4 | TTC13 | ENSP00000354961 | ENSP00000355621 | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | Tetratricopeptide repeat domain 13. | 0.472 |
NXPH1 | TTC13 | ENSP00000384551 | ENSP00000355621 | Neurexophilin-1; May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors. Belongs to the neurexophilin family. | Tetratricopeptide repeat domain 13. | 0.470 |
OR4K15 | TPGS1 | ENSP00000304077 | ENSP00000352265 | Olfactory receptor 4K15; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). | 0.564 |
OR4K15 | TTC13 | ENSP00000304077 | ENSP00000355621 | Olfactory receptor 4K15; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Tetratricopeptide repeat domain 13. | 0.620 |
RNF217 | TTC13 | ENSP00000428698 | ENSP00000355621 | Probable E3 ubiquitin-protein ligase RNF217; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates; Belongs to the RBR family. RNF217 subfamily. | Tetratricopeptide repeat domain 13. | 0.461 |
TPGS1 | OR4K15 | ENSP00000352265 | ENSP00000304077 | Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). | Olfactory receptor 4K15; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.564 |
TPGS1 | TTC13 | ENSP00000352265 | ENSP00000355621 | Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). | Tetratricopeptide repeat domain 13. | 0.574 |
TTC13 | BTBD17 | ENSP00000355621 | ENSP00000364515 | Tetratricopeptide repeat domain 13. | BTB/POZ domain-containing protein 17; BTB domain containing 17. | 0.491 |
TTC13 | CDC42EP5 | ENSP00000355621 | ENSP00000301200 | Tetratricopeptide repeat domain 13. | Cdc42 effector protein 5; Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42 (By similarity); Belongs to the BORG/CEP family. | 0.518 |
TTC13 | FAM122B | ENSP00000355621 | ENSP00000487221 | Tetratricopeptide repeat domain 13. | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | 0.496 |
TTC13 | LEO1 | ENSP00000355621 | ENSP00000299601 | Tetratricopeptide repeat domain 13. | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser- 5'-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox [...] | 0.475 |
TTC13 | MT-ND4 | ENSP00000355621 | ENSP00000354961 | Tetratricopeptide repeat domain 13. | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | 0.472 |
TTC13 | NXPH1 | ENSP00000355621 | ENSP00000384551 | Tetratricopeptide repeat domain 13. | Neurexophilin-1; May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors. Belongs to the neurexophilin family. | 0.470 |
TTC13 | OR4K15 | ENSP00000355621 | ENSP00000304077 | Tetratricopeptide repeat domain 13. | Olfactory receptor 4K15; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.620 |
TTC13 | RNF217 | ENSP00000355621 | ENSP00000428698 | Tetratricopeptide repeat domain 13. | Probable E3 ubiquitin-protein ligase RNF217; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates; Belongs to the RBR family. RNF217 subfamily. | 0.461 |
TTC13 | TPGS1 | ENSP00000355621 | ENSP00000352265 | Tetratricopeptide repeat domain 13. | Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). | 0.574 |