VTCN1 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
V-set domain containing T cell activation inhibitor 1; Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor- associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation (282 aa)
(Homo sapiens)
Predicted Functional Partners:
B and T lymphocyte associated; Lymphocyte inhibitory receptor which inhibits lymphocytes during [...] (289 aa)
interleukin 6 (interferon, beta 2); Cytokine with a wide variety of biological functions. It is [...] (212 aa)
cytotoxic T-lymphocyte-associated protein 4 (223 aa)
programmed cell death 1 ligand 2; Involved in the costimulatory signal, essential for T- cell p [...] (273 aa)
speckle-type POZ protein; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-pro [...] (374 aa)
forkhead box P3; Probable transcription factor. Plays a critical role in the control of immune [...] (431 aa)
CD8a molecule; Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing t [...] (235 aa)
programmed cell death 1; Inhibitory cell surface receptor involved in the regulation of T-cell [...] (288 aa)
triggering receptor expressed on myeloid cells-like 2; Cell surface receptor that may play a ro [...] (321 aa)
inducible T-cell co-stimulator ligand; Ligand for the T-cell-specific cell surface receptor ICO [...] (302 aa)
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