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CFAP58 CFAP58 CFAP43 CFAP43 TTC29 TTC29 CFAP70 CFAP70 TTC21A TTC21A CFAP61 CFAP61 ARMC2 ARMC2 WDR66 WDR66 CFAP44 CFAP44 QRICH2 QRICH2 CFAP69 CFAP69
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CFAP58Cilia and flagella associated protein 58; Belongs to the CFAP58 family. (872 aa)    
Predicted Functional Partners:
CFAP43
Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.
   
  
 0.691
TTC29
Tetratricopeptide repeat domain 29.
   
  
 0.671
CFAP70
Cilia and flagella associated protein 70; Belongs to the CFAP70 family.
   
 
 0.633
TTC21A
Tetratricopeptide repeat protein 21A; Intraflagellar transport (IFT)-associated protein required for spermatogenesis. Required for sperm flagellar formation and intraflagellar transport. Belongs to the TTC21 family.
   
  
 0.629
CFAP61
Cilia- and flagella-associated protein 61; May regulate cilium motility through its role in the assembly of the axonemal radial spokes.
   
  
 0.628
ARMC2
Armadillo repeat-containing protein 2; Required for sperm flagellum axoneme organization and function (By similarity). Involved in axonemal central pair complex assembly and/or stability (By similarity).
   
  
 0.613
WDR66
Cilia- and flagella-associated protein 251; Involved in spermatozoa motility. May also regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity).
   
  
 0.611
CFAP44
Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function.
   
  
 0.597
QRICH2
Glutamine-rich protein 2; Has an essential role in the formation of sperm flagella and flagellar structure maintainance. It acts as a suppressor of ubiquitination and degradation of proteins involved in flagellar development and motility.
   
 
 0.594
CFAP69
Cilia- and flagella-associated protein 69; Cilium- and flagellum-associated protein. In the olfactory epithelium, regulates the speed of activation and termination of the odor response and thus contributes to the robustness of olfactory transduction pathways (By similarity). Required for sperm flagellum assembly and stability.
   
  
 0.588
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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