STRINGSTRING
HHLA3 HHLA3 HHLA2 HHLA2 NMI NMI MAGEB5 MAGEB5 HHLA1 HHLA1 SLC10A5 SLC10A5 KIAA0040 KIAA0040
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HHLA3HERV-H LTR-associating 3. (121 aa)    
Predicted Functional Partners:
HHLA2
HERV-H LTR-associating protein 2; Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
      
 0.972
NMI
N-myc-interactor; May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5; Belongs to the NMI family.
    
   0.539
MAGEB5
Melanoma-associated antigen B5; MAGE family member B5.
      
 0.506
HHLA1
HERV-H LTR-associating 1.
      
 0.479
SLC10A5
Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5.
      
 0.430
KIAA0040
Uncharacterized protein KIAA0040; KIAA0040.
      
 0.402
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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