STRINGSTRING
GLT6D1 GLT6D1 CTSC CTSC STPG3 STPG3 SLFNL1 SLFNL1 TEX36 TEX36 GATA3 GATA3 OBP2A OBP2A SIGLEC5-2 SIGLEC5-2 SIGLEC5 SIGLEC5 DSPP DSPP SPPL2C SPPL2C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
GLT6D1Glycosyltransferase 6 domain containing 1; Belongs to the glycosyltransferase 6 family. (276 aa)    
Predicted Functional Partners:
CTSC
Dipeptidyl peptidase 1 exclusion domain chain; Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serine proteases such as elastase, cathepsin G and granzymes A and B. Can also activate neuraminidase and factor XIII; Belongs to the peptidase C1 family.
      
 0.753
STPG3
Protein STPG3; Sperm-tail PG-rich repeat containing 3.
      
 0.670
SLFNL1
Schlafen-like protein 1; Schlafen like 1.
   
  
 0.633
TEX36
Testis-expressed protein 36; Testis expressed 36.
      
 0.618
GATA3
Trans-acting T-cell-specific transcription factor GATA-3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.
      
 0.618
OBP2A
Odorant binding protein 2A; Belongs to the calycin superfamily. Lipocalin family.
      
 0.574
SIGLEC5-2
Sialic acid-binding Ig-like lectin 5; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
      
 0.549
SIGLEC5
Sialic acid binding Ig like lectin 5.
      
 0.549
DSPP
Dentin sialophosphoprotein; DSP may be an important factor in dentinogenesis. DPP may bind high amount of calcium and facilitate initial mineralization of dentin matrix collagen as well as regulate the size and shape of the crystals.
      
 0.548
SPPL2C
Signal peptide peptidase-like 2C; Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane.
      
 0.499
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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