STRINGSTRING
C1orf50 C1orf50 AHCY AHCY WDYHV1 WDYHV1 FAM200B FAM200B FAM183A FAM183A SVBP SVBP NIF3L1 NIF3L1 YBEY YBEY EPM2AIP1 EPM2AIP1 ZNF691 ZNF691 CCDC30 CCDC30
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C1orf50Uncharacterized protein C1orf50; Chromosome 1 open reading frame 50. (199 aa)    
Predicted Functional Partners:
AHCY
Adenosylhomocysteinase; Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.
   
   0.894
WDYHV1
Protein N-terminal glutamine amidohydrolase; Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested sec [...]
   
 
 0.574
FAM200B
Protein FAM200B; Family with sequence similarity 200 member B; Belongs to the FAM200 family.
   
  
 0.510
FAM183A
Protein FAM183A; Family with sequence similarity 183 member A; Belongs to the FAM183 family.
      
 0.506
SVBP
Small vasohibin-binding protein; Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin. This activity is critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning. Also required to enhance the solubility and secretion of VASH1 and VASH2. Plays a role in axon and excitatory synapse formation. Belongs to the SVBP family.
   
  
 0.454
NIF3L1
NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
   
  
 0.453
YBEY
Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in rRNA maturation.
   
    0.436
EPM2AIP1
EPM2A interacting protein 1.
   
   0.434
ZNF691
Zinc finger protein 691; May be involved in transcriptional regulation.
   
  
 0.420
CCDC30
Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family.
      
 0.416
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.