STRINGSTRING
XKRX XKRX KEL KEL VPS13A VPS13A IGFL4 IGFL4 TMEM234 TMEM234 XKR9 XKR9 TCP11L2 TCP11L2 FAM171B FAM171B HSFY1 HSFY1 CDYL2 CDYL2 TRAFD1 TRAFD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XKRXXK-related protein 2; XK related X-linked. (449 aa)    
Predicted Functional Partners:
KEL
Kell blood group glycoprotein; Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3.
      
 0.865
VPS13A
Vacuolar protein sorting-associated protein 13A; May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane.
   
 
 0.508
IGFL4
IGF like family member 4; Belongs to the IGFL family.
      
 0.472
TMEM234
Transmembrane protein 234; Belongs to the TMEM234 family.
      
 0.454
XKR9
XK-related protein 9; XK related 9.
      
 0.435
TCP11L2
T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.
   
  
 0.434
FAM171B
Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family.
      
 0.418
HSFY1
Heat shock transcription factor Y-linked 1; Belongs to the HSF family.
   
  
 0.413
CDYL2
Chromodomain Y like 2.
      
 0.405
TRAFD1
TRAF-type zinc finger domain-containing protein 1; Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity).
    
 
 0.402
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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