STRINGSTRING
CCDC158 CCDC158 TMEM236 TMEM236 TXLNB TXLNB NUP54 NUP54 NCLN NCLN PPEF2 PPEF2 HELQ HELQ SCGB2A1 SCGB2A1 PAFAH2 PAFAH2 ZNF615 ZNF615 C16orf71 C16orf71
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC158Coiled-coil domain containing 158. (1113 aa)    
Predicted Functional Partners:
TMEM236
Transmembrane protein 236.
   
  
 0.540
TXLNB
Beta-taxilin; Promotes motor nerve regeneration (By similarity). May be involved in intracellular vesicle traffic; Belongs to the taxilin family.
      
 0.516
NUP54
Nucleoporin p54; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.
      
 0.505
NCLN
Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family.
      
 0.490
PPEF2
Serine/threonine-protein phosphatase with EF-hands 2; May play a role in phototransduction. May dephosphorylate photoactivated rhodopsin. May function as a calcium sensing regulator of ionic currents, energy production or synaptic transmission.
   
 
 0.485
HELQ
Helicase POLQ-like; Single-stranded DNA-dependent ATPase and 5' to 3' DNA helicase. Involved in the repair of DNA cross-links and double-strand break (DSB) resistance. Participates in FANCD2- mediated repair. Forms a complex with POLN polymerase that participates in homologous recombination (HR) repair and is essential for cellular protection against DNA cross-links. Belongs to the helicase family. SKI2 subfamily.
   
  
 0.469
SCGB2A1
Mammaglobin-B; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.
   
   0.459
PAFAH2
Platelet-activating factor acetylhydrolase 2, cytoplasmic; Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme.
      
 0.458
ZNF615
Zinc finger protein 615; May be involved in transcriptional regulation.
   
 
 0.457
C16orf71
Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71.
   
  
 0.448
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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