STRING 9.1 
  SPP1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
SPP1
secreted phosphoprotein 1; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction (314 aa)
(Homo sapiens)
Predicted Functional Partners:
CD44
CD44 molecule (Indian blood group); Receptor for hyaluronic acid (HA). Mediates cell-cell and c [...] (742 aa)
     0.966
ITGB3
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); Integrin alpha-V/beta-3 is a recep [...] (788 aa)
      0.966
ITGAV
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); The alpha-V integrin [...] (1048 aa)
     0.946
FN1
fibronectin 1; Fibronectins bind cell surfaces and various compounds including collagen, fibrin [...] (2477 aa)
      0.937
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); I [...] (825 aa)
     0.932
BMP2
bone morphogenetic protein 2; Induces cartilage and bone formation (396 aa)
       0.927
RUNX2
runt-related transcription factor 2; Transcription factor involved in osteoblastic differentiat [...] (589 aa)
       0.927
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide); Integrin alpha-5/beta-1 is a recep [...] (1049 aa)
     0.919
ITGA9
integrin, alpha 9; Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. [...] (1035 aa)
      0.919
PTH
parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing [...] (115 aa)
       0.906
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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