node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD55 | PRTFDC1 | ENSP00000342295 | ENSP00000318602 | Ankyrin repeat domain 55. | Phosphoribosyltransferase domain-containing protein 1; Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.602 |
ANKRD55 | ZNF626 | ENSP00000342295 | ENSP00000469958 | Ankyrin repeat domain 55. | Zinc finger protein 626; May be involved in transcriptional regulation. | 0.614 |
GOLGA8J | ZNF626 | ENSP00000456401 | ENSP00000469958 | Golgin A8 family member J; Belongs to the GOLGA8 family. | Zinc finger protein 626; May be involved in transcriptional regulation. | 0.407 |
OR2AE1 | ZNF626 | ENSP00000313936 | ENSP00000469958 | Olfactory receptor 2AE1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Zinc finger protein 626; May be involved in transcriptional regulation. | 0.403 |
PRTFDC1 | ANKRD55 | ENSP00000318602 | ENSP00000342295 | Phosphoribosyltransferase domain-containing protein 1; Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Ankyrin repeat domain 55. | 0.602 |
PRTFDC1 | ZNF626 | ENSP00000318602 | ENSP00000469958 | Phosphoribosyltransferase domain-containing protein 1; Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Zinc finger protein 626; May be involved in transcriptional regulation. | 0.496 |
TRIM28 | ZNF486 | ENSP00000253024 | ENSP00000335042 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 486; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.536 |
TRIM28 | ZNF626 | ENSP00000253024 | ENSP00000469958 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 626; May be involved in transcriptional regulation. | 0.533 |
ZNF486 | TRIM28 | ENSP00000335042 | ENSP00000253024 | Zinc finger protein 486; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.536 |
ZNF486 | ZNF626 | ENSP00000335042 | ENSP00000469958 | Zinc finger protein 486; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 626; May be involved in transcriptional regulation. | 0.630 |
ZNF626 | ANKRD55 | ENSP00000469958 | ENSP00000342295 | Zinc finger protein 626; May be involved in transcriptional regulation. | Ankyrin repeat domain 55. | 0.614 |
ZNF626 | GOLGA8J | ENSP00000469958 | ENSP00000456401 | Zinc finger protein 626; May be involved in transcriptional regulation. | Golgin A8 family member J; Belongs to the GOLGA8 family. | 0.407 |
ZNF626 | OR2AE1 | ENSP00000469958 | ENSP00000313936 | Zinc finger protein 626; May be involved in transcriptional regulation. | Olfactory receptor 2AE1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.403 |
ZNF626 | PRTFDC1 | ENSP00000469958 | ENSP00000318602 | Zinc finger protein 626; May be involved in transcriptional regulation. | Phosphoribosyltransferase domain-containing protein 1; Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.496 |
ZNF626 | TRIM28 | ENSP00000469958 | ENSP00000253024 | Zinc finger protein 626; May be involved in transcriptional regulation. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.533 |
ZNF626 | ZNF486 | ENSP00000469958 | ENSP00000335042 | Zinc finger protein 626; May be involved in transcriptional regulation. | Zinc finger protein 486; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.630 |