STRINGSTRING
PFDN6 PFDN6 PFDN2 PFDN2 PFDN4 PFDN4 VBP1 VBP1 PDRG1 PDRG1 PFDN1 PFDN1 GATB GATB PFDN5 PFDN5 ENSCAFP00000046639 ENSCAFP00000046639 ENSCAFP00000057634 ENSCAFP00000057634 RPAP3 RPAP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PFDN6Prefoldin subunit 6; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity); Belongs to the prefoldin subunit beta family. (129 aa)    
Predicted Functional Partners:
PFDN2
Prefoldin subunit 2.
   
 
 0.977
PFDN4
Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.
   
 
 0.919
VBP1
Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.
   
 
 0.918
PDRG1
P53 and DNA damage regulated 1.
    
 
 0.917
PFDN1
Uncharacterized protein.
   
 
 0.900
GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.
      
 0.851
PFDN5
Uncharacterized protein.
   
 
 0.850
ENSCAFP00000046639
Uncharacterized protein.
   
 
 0.850
ENSCAFP00000057634
Uncharacterized protein.
   
 
 0.850
RPAP3
RNA polymerase II associated protein 3.
   
 
 0.836
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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