STRINGSTRING
MCHR2 MCHR2 PMCH PMCH MCHR1 MCHR1 CLNK CLNK CRYBG1 CRYBG1 UTS2 UTS2 NPB NPB SIM1 SIM1 LPAR2 LPAR2 GAL GAL TRH TRH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCHR2Melanin concentrating hormone receptor 2; Belongs to the G-protein coupled receptor 1 family. (338 aa)    
Predicted Functional Partners:
PMCH
Neuropeptide-glutamic acid-isoleucine; MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal.
   
 
 0.991
MCHR1
Melanin concentrating hormone receptor 1.
   
 
0.917
CLNK
Cytokine dependent hematopoietic cell linker.
      
 0.819
CRYBG1
Crystallin beta-gamma domain containing 1; Belongs to the beta/gamma-crystallin family.
    
 
 0.778
UTS2
Uncharacterized protein.
     
 0.768
NPB
Neuropeptide B.
     
 0.741
SIM1
SIM bHLH transcription factor 1.
   
  
 0.708
LPAR2
Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.703
GAL
Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.
   
 0.682
TRH
Thyrotropin releasing hormone.
     
 0.678
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.