STRINGSTRING
RAB25 RAB25 RAB11FIP2 RAB11FIP2 RAB11FIP1 RAB11FIP1 PI4KB PI4KB ARHGAP22 ARHGAP22 RAB11FIP3 RAB11FIP3 RAB11FIP4 RAB11FIP4 MYO5B MYO5B ZBTB7B ZBTB7B MYO5A MYO5A ITGAD ITGAD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB25Ras-related protein Rab-25; Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity). (213 aa)    
Predicted Functional Partners:
RAB11FIP2
RAB11 family interacting protein 2.
   
 
 0.913
RAB11FIP1
RAB11 family interacting protein 1.
   
 
 0.765
PI4KB
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
   
 
 0.751
ARHGAP22
Rho GTPase activating protein 22.
    
 
 0.722
RAB11FIP3
RAB11 family interacting protein 3.
    
 
 0.689
RAB11FIP4
RAB11 family interacting protein 4.
   
 
 0.684
MYO5B
Myosin VB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 
 0.668
ZBTB7B
Zinc finger and BTB domain containing 7B.
    
 
 0.649
MYO5A
Myosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 
 0.647
ITGAD
Integrin subunit alpha M; Belongs to the integrin alpha chain family.
      
 0.637
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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