STRINGSTRING
DDX39B DDX39B ALYREF ALYREF THOC5 THOC5 THOC2 THOC2 SARNP SARNP THOC6 THOC6 THOC1 THOC1 THOC7 THOC7 POLDIP3 POLDIP3 THOC3 THOC3 CHTOP CHTOP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDX39BSpliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...] (428 aa)    
Predicted Functional Partners:
ALYREF
Aly/REF export factor.
   
 0.996
THOC5
THO complex 5.
   
 0.952
THOC2
THO complex 2.
   
 0.948
SARNP
SAP domain containing ribonucleoprotein.
   
 0.940
THOC6
THO complex 6.
   
 0.920
THOC1
THO complex 1.
   
 0.914
THOC7
THO complex 7.
   
 0.908
POLDIP3
DNA polymerase delta interacting protein 3.
   
 0.904
THOC3
THO complex 3.
   
 0.883
CHTOP
Chromatin target of PRMT1.
   
 0.879
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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