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 | IL4 | interleukin 4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes (153 aa) |
| | (Homo sapiens) |
Predicted Functional Partners: |
 | IL4R | interleukin 4 receptor; Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1 [...] (825 aa) | | | | | • | • | • | | 0.999 |
 | IL2RG | interleukin 2 receptor, gamma (severe combined immunodeficiency); Common subunit for the recept [...] (369 aa) | | | | | • | • | • | | 0.999 |
 | IL13RA1 | interleukin 13 receptor, alpha 1; Binds IL13 with a low affinity. Together with IL4R-alpha can [...] (427 aa) | | | | | • | • | • | | 0.998 |
 | STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced; Carries out a dual f [...] (847 aa) | | | | | | • | • | | 0.995 |
 | IL2 | interleukin 2; Produced by T-cells in response to antigenic or mitogenic stimulation, this prot [...] (153 aa) | | | | | | • | • | | 0.993 |
 | CSF2 | colony stimulating factor 2 (granulocyte-macrophage); Cytokine that stimulates the growth and d [...] (144 aa) | | | | | | • | • | | 0.992 |
 | IL5 | interleukin 5 (colony-stimulating factor, eosinophil); Factor that induces terminal differentia [...] (134 aa) | | | | | | • | • | | 0.992 |
 | IL13 | interleukin 13; Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in reg [...] (146 aa) | | | | | | • | • | | 0.992 |
 | JAK2 | Janus kinase 2; Plays a role in leptin signaling and control of body weight (By similarity). Ty [...] (1132 aa) | | | | | | • | • | | 0.989 |
 | JAK3 | Janus kinase 3; Tyrosine kinase of the non-receptor type, involved in the interleukin-2 and int [...] (1124 aa) | | | | | | • | • | | 0.988 |
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