| Your Input: |
 | TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10; Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis (281 aa) |
| | (Homo sapiens) |
Predicted Functional Partners: |
 | CASP8 | caspase 8, apoptosis-related cysteine peptidase; Most upstream protease of the activation casca [...] (538 aa) | | | | | • | • | • | | 0.999 |
 | TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b; Receptor for the cytotoxic ligand TNFSF [...] (440 aa) | | | | | • | • | • | | 0.999 |
 | FADD | Fas (TNFRSF6)-associated via death domain; Apoptotic adaptor molecule that recruits caspase-8 o [...] (208 aa) | | | | | • | • | • | | 0.999 |
 | TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a; Receptor for the cytotoxic ligand TNFSF [...] (468 aa) | | | | | • | • | • | | 0.999 |
 | CFLAR | CASP8 and FADD-like apoptosis regulator; Apoptosis regulator protein which may function as a cr [...] (480 aa) | | | | | • | • | • | | 0.999 |
 | TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; Rece [...] (386 aa) | | | | | • | • | • | | 0.996 |
 | TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain; [...] (259 aa) | | | | | • | • | • | | 0.993 |
 | CASP10 | caspase 10, apoptosis-related cysteine peptidase; Involved in the activation cascade of caspase [...] (522 aa) | | | | | • | • | • | | 0.984 |
 | TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b; Acts as decoy receptor for RANKL and th [...] (401 aa) | | | | | • | • | • | | 0.970 |
 | TRADD | TNFRSF1A-associated via death domain; Adapter molecule for TNFRSF1A/TNFR1 that specifically ass [...] (312 aa) | | | | | | • | • | | 0.958 |
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