STRINGSTRING
LGB2 LGB2 LYZL6 LYZL6 LALBA LALBA RBP4 RBP4 CSN3 CSN3 CSN2 CSN2 LYZL4 LYZL4 TOP2B TOP2B KRT4 KRT4 CDC73 CDC73 PAF1 PAF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
LGB2Beta-lactoglobulin-2; Lactoglobulin is the primary component of whey, it binds retinol and is probably involved in the transport of that molecule. (181 aa)    
Predicted Functional Partners:
LYZL6
Lysozyme like 6; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.825
LALBA
Alpha-lactalbumin A; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.798
RBP4
Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane.
      
 0.633
CSN3
Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
   
 0.623
CSN2
Beta-casein; Important role in determination of the surface properties of the casein micelles.
   
  
 0.600
LYZL4
Lysozyme like 4; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.581
TOP2B
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
  
 0.569
KRT4
IF rod domain-containing protein; Belongs to the intermediate filament family.
    
 
 0.559
CDC73
Cell division cycle 73.
   
 0.470
PAF1
PAF1 homolog, Paf1/RNA polymerase II complex component.
   
 0.459
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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