node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IFNGR1 | IL12A | ENSECAP00000007472 | ENSECAP00000022221 | Interferon gamma receptor 1. | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | 0.719 |
IFNGR1 | IL12B | ENSECAP00000007472 | ENSECAP00000010803 | Interferon gamma receptor 1. | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. | 0.783 |
IFNGR1 | IL12RB1 | ENSECAP00000007472 | ENSECAP00000019388 | Interferon gamma receptor 1. | Interleukin 12 receptor subunit beta 1. | 0.580 |
IFNGR1 | IL23A | ENSECAP00000007472 | ENSECAP00000019716 | Interferon gamma receptor 1. | Interleukin-23 subunit alpha; Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tu [...] | 0.672 |
IFNGR1 | IL27RA | ENSECAP00000007472 | ENSECAP00000009925 | Interferon gamma receptor 1. | Interleukin 27 receptor subunit alpha. | 0.536 |
IFNGR1 | IL2RA | ENSECAP00000007472 | ENSECAP00000031916 | Interferon gamma receptor 1. | Interleukin 2 receptor subunit alpha. | 0.483 |
IL12A | IFNGR1 | ENSECAP00000022221 | ENSECAP00000007472 | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Interferon gamma receptor 1. | 0.719 |
IL12A | IL12B | ENSECAP00000022221 | ENSECAP00000010803 | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. | 0.995 |
IL12A | IL12RB1 | ENSECAP00000022221 | ENSECAP00000019388 | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Interleukin 12 receptor subunit beta 1. | 0.955 |
IL12A | IL12RB2 | ENSECAP00000022221 | ENSECAP00000014307 | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Interleukin 12 receptor subunit beta 2. | 0.935 |
IL12A | IL23A | ENSECAP00000022221 | ENSECAP00000019716 | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Interleukin-23 subunit alpha; Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tu [...] | 0.422 |
IL12A | IL23R | ENSECAP00000022221 | ENSECAP00000014880 | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Interleukin 23 receptor. | 0.707 |
IL12A | IL27RA | ENSECAP00000022221 | ENSECAP00000009925 | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Interleukin 27 receptor subunit alpha. | 0.771 |
IL12A | IL2RA | ENSECAP00000022221 | ENSECAP00000031916 | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Interleukin 2 receptor subunit alpha. | 0.674 |
IL12A | IL6ST | ENSECAP00000022221 | ENSECAP00000025735 | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Interleukin 6 signal transducer. | 0.769 |
IL12B | IFNGR1 | ENSECAP00000010803 | ENSECAP00000007472 | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. | Interferon gamma receptor 1. | 0.783 |
IL12B | IL12A | ENSECAP00000010803 | ENSECAP00000022221 | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | 0.995 |
IL12B | IL12RB1 | ENSECAP00000010803 | ENSECAP00000019388 | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. | Interleukin 12 receptor subunit beta 1. | 0.990 |
IL12B | IL12RB2 | ENSECAP00000010803 | ENSECAP00000014307 | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. | Interleukin 12 receptor subunit beta 2. | 0.971 |
IL12B | IL23A | ENSECAP00000010803 | ENSECAP00000019716 | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. | Interleukin-23 subunit alpha; Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tu [...] | 0.996 |