node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACVR1B | ACVR1C | ENSECAP00000009804 | ENSECAP00000017534 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.751 |
ACVR1B | ACVR2A | ENSECAP00000009804 | ENSECAP00000039913 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.922 |
ACVR1B | ACVR2B | ENSECAP00000009804 | ENSECAP00000052896 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.883 |
ACVR1B | FST | ENSECAP00000009804 | ENSECAP00000015558 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Follistatin; Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). | 0.648 |
ACVR1B | INHBA | ENSECAP00000009804 | ENSECAP00000019902 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Inhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. | 0.951 |
ACVR1B | INHBB | ENSECAP00000009804 | ENSECAP00000011917 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Inhibin subunit beta B. | 0.755 |
ACVR1B | NODAL | ENSECAP00000009804 | ENSECAP00000014634 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Nodal growth differentiation factor. | 0.611 |
ACVR1B | TGFB1 | ENSECAP00000009804 | ENSECAP00000009480 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] | 0.783 |
ACVR1B | TGFB2 | ENSECAP00000009804 | ENSECAP00000051244 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.494 |
ACVR1C | ACVR1B | ENSECAP00000017534 | ENSECAP00000009804 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.751 |
ACVR1C | ACVR2A | ENSECAP00000017534 | ENSECAP00000039913 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.981 |
ACVR1C | ACVR2B | ENSECAP00000017534 | ENSECAP00000052896 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.981 |
ACVR1C | INHBA | ENSECAP00000017534 | ENSECAP00000019902 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Inhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. | 0.977 |
ACVR1C | INHBB | ENSECAP00000017534 | ENSECAP00000011917 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Inhibin subunit beta B. | 0.976 |
ACVR1C | NODAL | ENSECAP00000017534 | ENSECAP00000014634 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Nodal growth differentiation factor. | 0.954 |
ACVR1C | TGFB1 | ENSECAP00000017534 | ENSECAP00000009480 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] | 0.781 |
ACVR1C | TGFB2 | ENSECAP00000017534 | ENSECAP00000051244 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.571 |
ACVR2A | ACVR1B | ENSECAP00000039913 | ENSECAP00000009804 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.922 |
ACVR2A | ACVR1C | ENSECAP00000039913 | ENSECAP00000017534 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.981 |
ACVR2A | ACVR2B | ENSECAP00000039913 | ENSECAP00000052896 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.903 |