STRINGSTRING
IL12A IL12A IL12B IL12B IL12RB1 IL12RB1 IL12RB2 IL12RB2 CNTFR CNTFR IL6R IL6R IL27RA IL27RA EBI3 EBI3 IL6ST IL6ST CSF3R CSF3R IL10RB IL10RB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (256 aa)    
Predicted Functional Partners:
IL12B
Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family.
    
 0.995
IL12RB1
Interleukin 12 receptor subunit beta 1.
   
 0.955
IL12RB2
Interleukin 12 receptor subunit beta 2.
    
 0.935
CNTFR
Ciliary neurotrophic factor receptor.
    
 0.813
IL6R
Interleukin 6 receptor.
    
 0.813
IL27RA
Interleukin 27 receptor subunit alpha.
   
 0.771
EBI3
Epstein-Barr virus induced 3.
    
 0.769
IL6ST
Interleukin 6 signal transducer.
    
 0.769
CSF3R
Colony stimulating factor 3 receptor.
  
 
  0.731
IL10RB
Interleukin 10 receptor subunit beta.
     
 0.721
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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