STRINGSTRING
ALDH2 ALDH2 ADH4 ADH4 ADH5 ADH5 ABAT ABAT ACSS2 ACSS2 ACSS1 ACSS1 ADH1C ADH1C MAOB MAOB AGXT2 AGXT2 ALDH6A1 ALDH6A1 AKR1B1 AKR1B1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ALDH2Aldehyde dehydrogenase, mitochondrial; Is capable of converting retinaldehyde to retinoic acid. (537 aa)    
Predicted Functional Partners:
ADH4
Alcohol dehydrogenase 4 isoform 2.
  
 0.953
ADH5
S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.950
ABAT
4-aminobutyrate aminotransferase, mitochondrial; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.944
ACSS2
Acetyl-coenzyme A synthetase, cytoplasmic isoform X1.
   
 0.943
ACSS1
Acetyl-coenzyme A synthetase.
   
 0.942
ADH1C
PKS_ER domain-containing protein.
  
 0.942
MAOB
Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity).
 
 
 
 0.939
AGXT2
Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.939
ALDH6A1
Methylmalonate-semialdehyde dehydrogenase acylating, mitochondrial isoform 1.
  
0.936
AKR1B1
Aldo-keto reductase family 1 member B1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosacharides, bile acids and xenobiotics substrates. Key enzyme in the polyol pathway, catalyzes reduction of glucose to sorbitol during hyperglycemia. Reduces steroids and their derivatives and prostaglandins. Displays low enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal. Catalyzes th [...]
 
 
 0.934
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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