STRINGSTRING
TFIP11 TFIP11 DHX15 DHX15 CRNKL1 CRNKL1 CDC40 CDC40 EFTUD2 EFTUD2 PRPF8 PRPF8 BUD31 BUD31 XAB2 XAB2 SYF2 SYF2 GCFC2 GCFC2 SNRPA1 SNRPA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (836 aa)    
Predicted Functional Partners:
DHX15
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15.
   
 0.995
CRNKL1
Crooked neck pre-mRNA splicing factor 1.
   
  0.980
CDC40
Pre-mRNA-processing factor 17.
   
 0.978
EFTUD2
116 kDa U5 small nuclear ribonucleoprotein component.
   
 
 0.968
PRPF8
Pre-mRNA processing factor 8.
   
 
 0.956
BUD31
Protein BUD31 homolog isoform X2.
    
 
 0.954
XAB2
XPA binding protein 2.
   
 0.944
SYF2
SYF2 pre-mRNA splicing factor.
    
  0.941
GCFC2
GC-rich sequence DNA-binding factor 2 isoform 1.
    
 0.925
SNRPA1
Small nuclear ribonucleoprotein polypeptide A.
    
 
 0.887
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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