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SLC5A1 SLC5A1 SLC2A2 SLC2A2 MFSD4B MFSD4B SLC1A1 SLC1A1 SLC15A1 SLC15A1 SLC1A7 SLC1A7 SLC1A5 SLC1A5 SLC1A2 SLC1A2 SLC1A6 SLC1A6 SLC1A3 SLC1A3 FABP2 FABP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
SLC5A1Sodium/glucose cotransporter 1; Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. (690 aa)    
Predicted Functional Partners:
SLC2A2
Solute carrier family 2, facilitated glucose transporter member 2; Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Also able to mediate the transport of dehydroascorbate; Belongs to the major fac [...]
   
  
 0.915
MFSD4B
Major facilitator superfamily domain containing 4B.
   
 0.831
SLC1A1
Amino acid transporter.
   
  
 0.825
SLC15A1
Peptide transporter 1.
  
  
 0.744
SLC1A7
Amino acid transporter.
   
  
 0.693
SLC1A5
Amino acid transporter.
   
  
 0.690
SLC1A2
Amino acid transporter.
   
  
 0.690
SLC1A6
Amino acid transporter.
   
  
 0.690
SLC1A3
Amino acid transporter.
   
  
 0.688
FABP2
Fatty acid-binding protein, intestinal; FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor (By similarity).
   
  
 0.654
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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