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EPHX1 EPHX1 CYP1A1 CYP1A1 CYP1B1 CYP1B1 CYP1A2 CYP1A2 LOC100739163 LOC100739163 GSTO1 GSTO1 A0A5G2R4D9_PIG A0A5G2R4D9_PIG MGST3 MGST3 GSTA4 GSTA4 GSTM3 GSTM3 MGST1 MGST1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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EPHX1Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Belongs to the peptidase S33 family. (452 aa)    
Predicted Functional Partners:
CYP1A1
Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.971
CYP1B1
Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.
   
 0.961
CYP1A2
Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family.
   
 0.957
LOC100739163
Glutathione S-transferase P; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity); Belongs to the GST superfamily. Pi family.
   
 
 0.947
GSTO1
Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family.
   
 0.945
A0A5G2R4D9_PIG
Glutathione S-transferase.
   
 
 0.944
MGST3
Microsomal glutathione S-transferase 3.
   
 0.943
GSTA4
Glutathione S-transferase alpha 4.
   
 
 0.942
GSTM3
Glutathione S-transferase.
   
 
 0.942
MGST1
Microsomal glutathione S-transferase 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the MAPEG family.
   
 
 0.940
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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