node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADCY8 | ADCY9 | ENSSSCP00000048237 | ENSSSCP00000050422 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.640 |
ADCY8 | ENPP1 | ENSSSCP00000048237 | ENSSSCP00000039332 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.662 |
ADCY8 | ENPP3 | ENSSSCP00000048237 | ENSSSCP00000029207 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. | 0.658 |
ADCY8 | ITPA | ENSSSCP00000048237 | ENSSSCP00000054471 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.908 |
ADCY8 | NME1 | ENSSSCP00000048237 | ENSSSCP00000046889 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Nucleoside diphosphate kinase. | 0.662 |
ADCY8 | NME3 | ENSSSCP00000048237 | ENSSSCP00000008561 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Nucleoside diphosphate kinase. | 0.662 |
ADCY8 | NME6 | ENSSSCP00000048237 | ENSSSCP00000012100 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Nucleoside diphosphate kinase. | 0.658 |
ADCY8 | NUDT2 | ENSSSCP00000048237 | ENSSSCP00000011711 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Asymmetrically hydrolyzes Ap4A to yield AMP and ATP. Plays a major role in maintaining homeostasis. | 0.913 |
ADCY9 | ADCY8 | ENSSSCP00000050422 | ENSSSCP00000048237 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | 0.640 |
ADCY9 | ENPP1 | ENSSSCP00000050422 | ENSSSCP00000039332 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.659 |
ADCY9 | ENPP3 | ENSSSCP00000050422 | ENSSSCP00000029207 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. | 0.658 |
ADCY9 | ITPA | ENSSSCP00000050422 | ENSSSCP00000054471 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.900 |
ADCY9 | NME1 | ENSSSCP00000050422 | ENSSSCP00000046889 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Nucleoside diphosphate kinase. | 0.658 |
ADCY9 | NME3 | ENSSSCP00000050422 | ENSSSCP00000008561 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Nucleoside diphosphate kinase. | 0.658 |
ADCY9 | NME6 | ENSSSCP00000050422 | ENSSSCP00000012100 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Nucleoside diphosphate kinase. | 0.658 |
ADCY9 | NUDT2 | ENSSSCP00000050422 | ENSSSCP00000011711 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Asymmetrically hydrolyzes Ap4A to yield AMP and ATP. Plays a major role in maintaining homeostasis. | 0.939 |
CTPS1 | CTPS2 | ENSSSCP00000050806 | ENSSSCP00000061342 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.956 |
CTPS1 | ENPP1 | ENSSSCP00000050806 | ENSSSCP00000039332 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.926 |
CTPS1 | ENPP3 | ENSSSCP00000050806 | ENSSSCP00000029207 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. | 0.907 |
CTPS1 | ITPA | ENSSSCP00000050806 | ENSSSCP00000054471 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.764 |