STRINGSTRING
PRM1 PRM1 PRM2 PRM2 ODF1 ODF1 SYCP2 SYCP2 ELSPBP1 ELSPBP1 BSP1 BSP1 FSCN3 FSCN3 SPMI SPMI SPESP1 SPESP1 TNP2 TNP2 PSP-I PSP-I
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PRM1Sperm protamine P1; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. (47 aa)    
Predicted Functional Partners:
PRM2
Protamine-2; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.
   
  
 0.704
ODF1
Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.
   
  
 0.557
SYCP2
Synaptonemal complex protein 2.
      
 0.541
ELSPBP1
Epididymal sperm-binding protein 1; Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation. Has phosphorylcholine-binding activity.
   
  
 0.513
BSP1
Seminal plasma protein pB1; May form a complex with spermadhesin AQN-1 which possesses phosphorylcholine-binding activity.
      
 0.457
FSCN3
Fascin.
      
 0.457
SPMI
Seminal plasma sperm motility inhibitor; Inhibitor of sperm motility.
   
  
 0.455
SPESP1
Uncharacterized protein.
      
 0.455
TNP2
Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
   
  
 0.438
PSP-I
Major seminal plasma glycoprotein PSP-I; Not yet identified, major porcine seminal plasma protein. Can bind soybean trypsin inhibitor after deglycosylation.
   
  
 0.430
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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