SDHAF2 protein (Homo sapiens) - STRING network view

STRING 9.05

SDHAF2 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	SDHAF2	succinate dehydrogenase complex assembly factor 2; Required for insertion of FAD cofactor into SDHA, the catalytic subunit of succinate dehydrogenase (SDH). SDH is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). In is unclear whether it participates in the chemistry of FAD attachment (enzymatic function) or acts as a chaperone that maintains SDHA in a conformation that is susceptible to autocatalytic FAD attachment (166 aa)
		(Homo sapiens)
Predicted Functional Partners:
	SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp); Flavoprotein (FP) subunit of suc [...] (664 aa)	•	•	•	0.958
	SDHD	succinate dehydrogenase complex, subunit D, integral membrane protein; Membrane-anchoring subun [...] (159 aa)	•		•	0.790
	SDHC	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa; Mono-heme cytochr [...] (169 aa)	•		•	0.720
	SDHB	succinate dehydrogenase complex, subunit B, iron sulfur (Ip); Iron-sulfur protein (IP) subunit [...] (280 aa)	•		•	0.697
	PSG5	pregnancy specific beta-1-glycoprotein 5 (335 aa)			•	0.613

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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