CD14 protein (Homo sapiens) - STRING network view

STRING 9.05

CD14 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	CD14	CD14 molecule; Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (375 aa)
		(Homo sapiens)
Predicted Functional Partners:
	LBP	lipopolysaccharide binding protein; Binds to the lipid A moiety of bacterial lipopolysaccharide [...] (481 aa)		•	•	•	0.998
	TLR2	toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial l [...] (784 aa)	•	•	•	•	0.998
	TLR4	toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to ba [...] (839 aa)	•	•	•	•	0.991
	LY96	lymphocyte antigen 96; Cooperates with TLR4 in the innate immune response to bacterial lipopoly [...] (160 aa)	•		•	•	0.988
	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific); The production of the second messenge [...] (1265 aa)	•		•	•	0.956

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Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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