RND1 protein (Homo sapiens) - STRING network view

STRING 9.05

RND1 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	RND1	Rho family GTPase 1; Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments (232 aa)
		(Homo sapiens)
Predicted Functional Partners:
	PLXNB1	plexin B1; Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the a [...] (2135 aa)	•	•	•	0.999
	PLXNA2	plexin A2; Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent [...] (1894 aa)	•	•	•	0.998
	PLXNA1	plexin A1; Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 [...] (1873 aa)	•	•	•	0.995
	GRB7	growth factor receptor-bound protein 7; Interacts with the cytoplasmic domain of the epidermal [...] (532 aa)	•		•	0.970
	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain [...] (862 aa)		•	•	0.970

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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