CD34 protein (Homo sapiens) - STRING network view

STRING 9.05

CD34 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	CD34	CD34 molecule; Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins (385 aa)
		(Homo sapiens)
Predicted Functional Partners:
	SELL	selectin L; Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial [...] (385 aa)		•	•	0.984
	MYB	v-myb myeloblastosis viral oncogene homolog (avian); Transcriptional activator; DNA-binding pro [...] (761 aa)		•	•	0.945
	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); Integrins alpha-4/beta-1 [...] (1032 aa)			•	0.927
	HLA-B*40	HLA class I histocompatibility antigen, B-48 alpha chain Precursor (MHC class I antigen B*48)(B [...] (362 aa)			•	0.924
	SELP	selectin P (granule membrane protein 140kDa, antigen CD62); Ca(2+)-dependent receptor for myelo [...] (830 aa)	•		•	0.911

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Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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