NEK2 protein (Homo sapiens) - STRING network view

STRING 9.05

NEK2 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	NEK2	NIMA (never in mitosis gene a)-related kinase 2; Protein kinase that is involved in mitotic regulation. May have a role at the G2-M transition. May also play a role in meiosis. Isoform 1 but not isoform 2 appears to play a role in centrosome splitting. Isoform 1 phosphorylates and activates NEK11 in G1/S-arrested cells. Isoform 2, which is not present in the nucleolus, does not (445 aa)
		(Homo sapiens)
Predicted Functional Partners:
	CDC16	cell division cycle 16 homolog (S. cerevisiae); Component of the anaphase promoting complex/cyc [...] (620 aa)		•	•	•		0.998
	CDC26	cell division cycle 26 homolog (S. cerevisiae); Component of the anaphase promoting complex/cyc [...] (85 aa)		•	•			0.998
	CEP250	centrosomal protein 250kDa; Probably plays an important role in centrosome cohesion during inte [...] (2442 aa)		•	•	•		0.997
	CDK1	cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is [...] (297 aa)	•		•	•	•	0.986
	UBE2C	ubiquitin-conjugating enzyme E2C; Catalyzes the covalent attachment of ubiquitin to other prote [...] (179 aa)	•		•	•		0.985

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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