NRG3 protein (Homo sapiens) - STRING network view

STRING 9.05

NRG3 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	NRG3	neuregulin 3; Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes (696 aa)
		(Homo sapiens)
Predicted Functional Partners:
	ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); Specifically binds and is act [...] (1308 aa)	•	•	•	0.978
	CADPS2	Ca++-dependent secretion activator 2; Calcium-binding protein involved in exocytosis of vesicle [...] (1255 aa)			•	0.796
	AUTS2	autism susceptibility candidate 2 (1259 aa)			•	0.778
	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A; Binds to actin filaments (F-actin) an [...] (1098 aa)			•	0.675
	DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; May play a role in a signali [...] (763 aa)			•	0.659
	ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian); Binds and is activated by ne [...] (1342 aa)			•	0.659
	MARCH7	membrane-associated ring finger (C3HC4) 7; E3 ubiquitin-protein ligase which may specifically e [...] (704 aa)			•	0.651
	PVALB	parvalbumin; In muscle, the calcium-binding protein parvalbumin is thought to be involved in mu [...] (110 aa)			•	0.577
	AREGB	amphiregulin B; Bifunctional growth-modulating glycoprotein. Inhibits growth of several human c [...] (252 aa)			•	0.563
	AREG	amphiregulin; Bifunctional growth-modulating glycoprotein. Inhibits growth of several human car [...] (252 aa)			•	0.563

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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