STRINGSTRING
ZBTB18 ZBTB18 YPEL YPEL TCF19 TCF19 ZNF445 ZNF445 ZFHX4 ZFHX4 SOX4 SOX4 TFAP4 TFAP4 ACOT7 ACOT7 FOXJ3 FOXJ3 CCNT2 CCNT2 CDK17 CDK17
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB18Zinc finger and BTB domain-containing protein 18; Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. May [...] (531 aa)    
Predicted Functional Partners:
YPEL
Protein yippee-like; Belongs to the yippee family.
      
 0.626
TCF19
Transcription factor 19.
    
 
 0.554
ZNF445
Zinc finger protein 445.
   
 
0.512
ZFHX4
Zinc finger homeobox 4.
    
 
 0.501
SOX4
Transcription factor SOX.
    
 
 0.500
TFAP4
Transcription factor AP-4.
    
 
 0.498
ACOT7
Uncharacterized protein.
    
 
 0.490
FOXJ3
Forkhead box J3.
   
 
 0.486
CCNT2
Cyclin T2; Belongs to the cyclin family.
    
 
 0.485
CDK17
Cyclin dependent kinase 17.
    
 
 0.474
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
Server load: low (28%) [HD]