STRINGSTRING
PANK3 PANK3 COASY COASY PPCS PPCS VNN1 VNN1 VNN2 VNN2 ENPP1 ENPP1 PANK2 PANK2 PANK1 PANK1 ENPP3 ENPP3 CCDC30 CCDC30 PON3 PON3
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PANK3Pantothenate kinase 3; Plays a role in the physiological regulation of coenzyme A (CoA) levels; Belongs to the type II pantothenate kinase family. (370 aa)    
Predicted Functional Partners:
COASY
Coenzyme A synthase.
    
 0.958
PPCS
Phosphopantothenoylcysteine synthetase.
     
 0.957
VNN1
Pantetheinase; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine; Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.
     
 0.909
VNN2
Vanin 2.
     
 0.909
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
     
 0.908
PANK2
Pantothenate kinase 2.
  
  
0.902
PANK1
Pantothenate kinase 1.
  
  
0.902
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic [...]
     
 0.900
CCDC30
Coiled-coil domain containing 30.
     
 0.590
PON3
Paraoxonase 3.
   
  
 0.587
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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