STRINGSTRING
LAX1 LAX1 TRAT1 TRAT1 LIME1 LIME1 FAM192A FAM192A FCRLA FCRLA POU2AF1 POU2AF1 SH2D4B SH2D4B CLEC17A CLEC17A ELSPBP1 ELSPBP1 MZB1 MZB1 GAPT GAPT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
LAX1Lymphocyte transmembrane adapter 1; Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells. (387 aa)    
Predicted Functional Partners:
TRAT1
T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
   
  
 0.706
LIME1
Uncharacterized protein.
      
 0.686
FAM192A
Family with sequence similarity 192 member A.
      
 0.663
FCRLA
Fc receptor like A.
      
 0.596
POU2AF1
POU domain class 2-associating factor 1; Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers (By similarity).
   
  
 0.578
SH2D4B
SH2 domain containing 4B.
      
 0.576
CLEC17A
Uncharacterized protein.
      
 0.569
ELSPBP1
Epididymal sperm binding protein 1.
      
 0.536
MZB1
Marginal zone B- and B1-cell-specific protein; Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity). Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion, and integrin activation (By similarity).
   
  
 0.505
GAPT
GRB2 binding adaptor protein, transmembrane.
   
  
 0.496
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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